Enantioselective diamination with novel chiral hypervalent iodine catalysts.

ABSTRACT: Vicinal diamines constitute one the most important functional motif in organic chemistry because of its wide occurrence in a variety of biological and pharmaceutical molecules. We report an efficient metal-free, highly stereoselective intramolecular diamination using a novel chiral hypervalent iodine reagent together with its application as an efficient catalyst for the synthesis of diamines.

SUBMITTER: Mizar P 

PROVIDER: S-EPMC4736455 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature