Differential involvement of cortical and cerebellar areas using dominant and nondominant hands: An FMRI study.

ABSTRACT: Motor fMRI studies, comparing dominant (DH) and nondominant (NDH) hand activations have reported mixed findings, especially for the extent of ipsilateral (IL) activations and their relationship with task complexity. To date, no study has directly compared DH and NDH activations using an event-related visually guided dynamic power-grip paradigm with parametric (three) forces (GF) in healthy right-handed subjects. We implemented a hierarchical statistical approach aimed to: (i) identify the main effect networks engaged when using either hand; (ii) characterise DH/NDH responses at different GFs; (iii) assess contralateral (CL)/IL-specific and hemisphere-specific activations. Beyond confirming previously reported results, this study demonstrated that increasing GF has an effect on motor respon

SUBMITTER: Alahmadi AA 

PROVIDER: S-EPMC4737094 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature