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Associative Recognition Memory Awareness Improved by Theta-Burst Stimulation of Frontopolar Cortex.


ABSTRACT: Neuroimaging and lesion studies have implicated specific prefrontal cortex locations in subjective memory awareness. Based on this evidence, a rostrocaudal organization has been proposed whereby increasingly anterior prefrontal regions are increasingly involved in memory awareness. We used theta-burst transcranial magnetic stimulation (TBS) to temporarily modulate dorsolateral versus frontopolar prefrontal cortex to test for distinct causal roles in memory awareness. In three sessions, participants received TBS bilaterally to frontopolar cortex, dorsolateral prefrontal cortex, or a control location prior to performing an associative-recognition task involving judgments of memory awareness. Objective memory performance (i.e., accuracy) did not differ based on stimulation location. In contra

SUBMITTER: Ryals AJ 

PROVIDER: S-EPMC4737609 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature