Sandwich-format 3D printed microfluidic mixers: a flexible platform for multi-probe analysis.

ABSTRACT: We report on a microfluidic mixer fabrication platform that increases the versatility and flexibility of mixers for biomolecular applications. A sandwich-format design allows the application of multiple spectroscopic probes to the same mixer. A polymer spacer is 'sandwiched' between two transparent windows, creating a closed microfluidic system. The channels of the mixer are defined by regions in the polymer spacer that lack material and therefore the polymer need not be transparent in the spectral region of interest. Suitable window materials such as CaF2 make the device accessible to a wide range of optical probe wavelengths, from the deep UV to the mid-IR. In this study, we use a commercially available 3D printer to print the polymer spacers to apply three different channel designs into

SUBMITTER: Kise DP 

PROVIDER: S-EPMC4737954 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature