International Consortium on Mammographic Density: Methodology and population diversity captured across 22 countries.

ABSTRACT: Mammographic density (MD) is a quantitative trait, measurable in all women, and is among the strongest markers of breast cancer risk. The population-based epidemiology of MD has revealed genetic, lifestyle and societal/environmental determinants, but studies have largely been conducted in women with similar westernized lifestyles living in countries with high breast cancer incidence rates. To benefit from the heterogeneity in risk factors and their combinations worldwide, we created an International Consortium on Mammographic Density (ICMD) to pool individual-level epidemiological and MD data from general population studies worldwide. ICMD aims to characterize determinants of MD more precisely, and to evaluate whether they are consistent across populations worldwide. We included 11755 wome

SUBMITTER: McCormack VA 

PROVIDER: S-EPMC4738079 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature