Emerging risk factors and the dose-response relationship between physical activity and lone atrial fibrillation: a prospective case-control study.

ABSTRACT:

Aims

The role of high-intensity exercise and other emerging risk factors in lone atrial fibrillation (Ln-AF) epidemiology is still under debate. The aim of this study was to analyse the contribution of each of the emerging risk factors and the impact of physical activity dose in patients with Ln-AF.

Methods and results

Patients with Ln-AF and age- and sex-matched healthy controls were included in a 2:1 prospective case-control study. We obtained clinical and anthropometric data transthoracic echocardiography, lifetime physical activity questionnaire, 24-h ambulatory blood pressure monitoring, Berlin questionnaire score, and, in patients at high risk for obstructive sleep apnoea (OSA) syndrome, a polysomnography. A total of 115 cases and 57 controls were enrolled. Conditional

SUBMITTER: Calvo N 

PROVIDER: S-EPMC4739323 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature