A preliminary method development study to identify potential stroke biomarkers in plasma using multiple chromatographies with nanoLC-ESIMS detection.

ABSTRACT: Stroke is the leading cause of disability in the USA. Rapid, reliable diagnosis via a point-of-care blood test may facilitate earlier treatment to reduce disability. We have recently reported detailed methods of chromatographic separations of plasma samples coupled with nanoESI-ion trap a list of proteins which are viable candidates for further investigation as stroke biomarkers.

SUBMITTER: Kodali P 

PROVIDER: S-EPMC4739646 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature