Retinal Oximetry with Scanning Laser Ophthalmoscope in Infants.

ABSTRACT:

Purpose

Dual wavelength retinal oximetry has been developed for adults, but is not available for infants. Retinal oximetry may provide insight into the pathophysiology of oxygen-mediated diseases like retinopathy of prematurity. More insight in the oxygen metabolism of the retina in infants may provide valuable clues for better understanding and subsequent prevention or treatment of the disease. The measurements of oxygen saturation are obtained with two fundus images simultaneously captured in two different wavelengths of light. The comparison in light absorption of oxygenated and deoxygenated hemoglobin can be used to estimate the oxygen saturation within the retinal vessels by means of a software algorithm. This study aims to make retinal oximetry available for neonates. The fir

SUBMITTER: Vehmeijer WB 

PROVIDER: S-EPMC4740427 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature