Ethnic differences in cross-sectional associations between impaired glucose regulation, identified by oral glucose tolerance test or HbA1c values, and cardiovascular disease in a cohort of European and South Asian origin.

ABSTRACT:

Aims

We contrasted impaired glucose regulation (prediabetes) prevalence, defined according to oral glucose tolerance test or HbA1c values, and studied cross-sectional associations between prediabetes and subclinical/clinical cardiovascular disease (CVD) in a cohort of European and South Asian origin.

Methods

For 682 European and 520 South Asian men and women, aged 58-85 years, glycaemic status was determined by oral glucose tolerance test or HbA1c thresholds. Questionnaires, record review, coronary artery calcification scores and cerebral magnetic resonance imaging established clinical plus subclinical coronary heart and cerebrovascular disease.

Results

Prediabetes was more prevalent in South Asian participants when defined by HbA1c rather than by oral glucose toleran

SUBMITTER: Eastwood SV 

PROVIDER: S-EPMC4740925 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature