The Language Profile of Behavioral Variant Frontotemporal Dementia.

ABSTRACT:

Background

The language profile of behavioral variant frontotemporal dementia (bvFTD) remains to be fully defined.

Objective

We aimed to quantify the extent of language deficits in this patient group.

Methods

We assessed a cohort of patients with bvFTD (n = 24) in relation to patients with semantic variant primary progressive aphasia (svPPA; n = 14), nonfluent variant primary progressive aphasia (nfvPPA; n = 18), and healthy age-matched individuals (n = 24) cross-sectionally and longitudinally using a comprehensive battery of language and general neuropsychological tests. Neuroanatomical associations of language performance were assessed using voxel-based morphometry of patients' brain magnetic resonance images.

Results

Relative to healthy controls, and after a

SUBMITTER: Hardy CJ 

PROVIDER: S-EPMC4740928 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature