Association of PNPLA3 rs738409 and TM6SF2 rs58542926 with health services utilization in a population-based study.

ABSTRACT:

Background

Hepatic steatosis confers an increased risk of metabolic and cardiovascular disease and higher health services use. Associations of the single nucleotide polymorphisms (SNP) PNPLA3 rs738409 and TM6SF2 rs58542926 with hepatic steatosis have recently been established. This study investigates the association between rs738409 and rs58542926 with health services utilization in a general population.

Methods

Data of 3759 participants from Study of Health in Pomerania (SHIP), a population-based study in Germany, were obtained. The annual number of outpatient visits, hospitalization and length of hospital stay was regressed on rs738409 and rs58542926 and adjusted for socio-economic factors, lifestyle habits, clinical factors, and health status.

Results

Minor allele

SUBMITTER: Kopp J 

PROVIDER: S-EPMC4741011 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature