Home Screening for Bacterial Vaginosis to Prevent Sexually Transmitted Diseases.

ABSTRACT:

Background

Longitudinal studies have consistently found a significant association between bacterial vaginosis (BV) and acquisition of sexually transmitted diseases. However, there are limited prospective data to confirm these findings.

Methods

We conducted a prospective, randomized, open-label trial of home screening and treatment of young women with asymptomatic BV who were also at high risk for sexually transmitted diseases. These women were screened every 2 months for 12 months and randomized to treatment with oral metronidazole 500 mg twice daily for 7 days or observation alone. The primary outcome was the incidence of gonorrhea and/or chlamydia.

Results

A total of 1365 subjects were enrolled in the study across 10 sites. Adherence with mailing specimens obtained

SUBMITTER: Schwebke JR 

PROVIDER: S-EPMC4741364 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature