Random plasma glucose in early pregnancy is a better predictor of gestational diabetes diagnosis than maternal obesity.

ABSTRACT:

Aims/hypothesis

Asymptomatic pregnant women are screened for gestational diabetes (GDM) at 24-28 weeks' gestation. Recent guidelines also recommend screening early in gestation to identify undiagnosed pre-existing overt diabetes. We assessed the performance of random plasma glucose (RPG) testing at antenatal booking in predicting GDM diagnosis later in pregnancy.

Methods

Data from 25,543 consecutive singleton pregnancies at the Rosie Hospital in Cambridge (UK) were obtained from hospital electronic records as a service evaluation. All women were invited for an antenatal RPG (12-16 weeks) and a 50 g glucose challenge test (GCT; 24-28 weeks) with a 75 g OGTT if GCT >7.7 mmol/l (139 mg/dl).

Results

At booking, 17,736 women had an RPG that was able to predict GDM (receive

SUBMITTER: Meek CL 

PROVIDER: S-EPMC4742503 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature