Hospitalization rates in patients switched from oral anti-psychotics to aripiprazole once-monthly: final efficacy analysis.

ABSTRACT:

Objective

To compare hospitalization rates in patients with schizophrenia treated prospectively with aripiprazole once-monthly 400 mg (AOM 400; an extended-release injectable suspension) vs the same patients' retrospective rates with their prior oral anti-psychotic therapy.

Research design and methods

Multi-center, open-label, mirror-image, naturalistic study in a community setting in North America. Patients who required a change in treatment and/or would benefit from long-acting injectable anti-psychotic therapy were treated prospectively for 6 months with AOM 400. Retrospective data on hospitalization rates were obtained.

Clinical trial registration

ClinicalTrials.gov: NCT01432444.

Main outcome measures

The proportion of patients with ≥ 1 psychiatric inpatien

SUBMITTER: Kane JM 

PROVIDER: S-EPMC4743596 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature