Discrimination between bacterial species by ratiometric analysis of their carbohydrate binding profile.

ABSTRACT: Antibiotic resistance is a global health concern meaning there is an urgent need for new treatments and diagnostics. Here glycosylated surfaces are used to profile the binding patterns of a range of Gram-negative, Gram-positive and mycobacteria. This enables the creation of 'barcodes' to enable identification and discrimination between the strains, which could not be achieved by single-point glycan binding and offers a new concept in bacteria detection.

SUBMITTER: Otten L 

PROVIDER: S-EPMC4743676 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature