Recruitment of the left precentral gyrus in reading epilepsy: A multimodal neuroimaging study.

ABSTRACT:

Purpose

In a previous study, we investigated a 42-year-old male patient with primary reading epilepsy using continuous video-electroencephalography (EEG). Reading tasks induced left parasagittal spikes with a higher spike frequency when the phonological reading pathway was recruited compared to the lexical one. Here, we seek to localize the epileptogenic focus in the same patient as a function of reading pathway using multimodal neuroimaging.

Methods and results

The participant read irregular words and nonwords presented in a block-design paradigm during magnetoencephalography (MEG), functional near-infrared spectroscopy (fNIRS), and functional magnetic resonance imaging (fMRI) recordings, all combined with EEG. Spike analyses from MEG, fNIRS, and fMRI-EEGs data revealed an

SUBMITTER: Safi D 

PROVIDER: S-EPMC4744333 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature