Global Mortality Impact of the 1957-1959 Influenza Pandemic.

ABSTRACT:

Background

Quantitative estimates of the global burden of the 1957 influenza pandemic are lacking. Here we fill this gap by modeling historical mortality statistics.

Methods

We used annual rates of age- and cause-specific deaths to estimate pandemic-related mortality in excess of background levels in 39 countries in Europe, the Asia-Pacific region, and the Americas. We modeled the relationship between excess mortality and development indicators to extrapolate the global burden of the pandemic.

Results

The pandemic-associated excess respiratory mortality rate was 1.9/10,000 population (95% confidence interval [CI], 1.2-2.6 cases/10,000 population) on average during 1957-1959. Excess mortality rates varied 70-fold across countries; Europe and Latin America experienced t

SUBMITTER: Viboud C 

PROVIDER: S-EPMC4747626 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature