Biological and psychosocial risk factors for psychotic major depression.

ABSTRACT:

Aims

Few studies have investigated risk factors for psychotic major depression (PMD). We aimed to investigate the biological and psychosocial risk factors associated with PMD compared with other psychotic disorders.

Methods

Based on the aetiology and ethnicity in schizophrenia and other psychoses (ÆSOP) study, we used a case-control study to identify and recruit, at baseline and 10-year follow-up, all first episode cases of psychosis, presenting for the first time to specialist mental health services in defined catchment areas in the UK. Population-based controls were recruited from the same areas. Data were collected on: sociodemographics; social isolation; childhood adversity; life events; minor physical anomalies; and neurological soft signs.

Results

Living alone (

SUBMITTER: Heslin M 

PROVIDER: S-EPMC4748002 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature