A specialist herbivore pest adaptation to xenobiotics through up-regulation of multiple Cytochrome P450s.

ABSTRACT: The adaptation of herbivorous insects to their host plants is hypothesized to be intimately associated with their ubiquitous development of resistance to synthetic pesticides. However, not much is known about the mechanisms underlying the relationship between detoxification of plant toxins and synthetic pesticides. To address this knowledge gap, we used specialist pest Colorado potato beetle (CPB) and its host plant, potato, as a model system. Next-generation sequencing (454 pyrosequencing) was performed to reveal the CPB transcriptome. Differential expression patterns of cytochrome P450 complement (CYPome) were analyzed between the susceptible (S) and imidacloprid resistant (R) beetles. We also evaluated the global transcriptome repertoire of CPB CYPome in response to the challenge by pot

SUBMITTER: Zhu F 

PROVIDER: S-EPMC4748221 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature