Drug Eluting Stents for Malignant Airway Obstruction: A Critical Review of the Literature.

ABSTRACT: Lung cancer being the most prevalent malignancy in men and the 3(rd) most frequent in women is still associated with dismal prognosis due to advanced disease at the time of diagnosis. Novel targeted therapies are already on the market and several others are under investigation. However non-specific cytotoxic agents still remain the cornerstone of treatment for many patients. Central airways stenosis or obstruction may often complicate and decrease quality of life and survival of these patients. Interventional pulmonology modalities (mainly debulking and stent placement) can alleviate symptoms related to airways stenosis and improve the quality of life of patients. Mitomycin C and sirolimus have been observed to assist a successful stent placement by reducing granuloma tissue formation. Add

SUBMITTER: Hohenforst-Schmidt W 

PROVIDER: S-EPMC4749359 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature