Ontology highlight
ABSTRACT:
SUBMITTER: Schadich E
PROVIDER: S-EPMC4749771 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Schadich Ermin E Hlaváč Jan J Volná Tereza T Varanasi Lakshman L Hajdúch Marián M Džubák Petr P
BioMed research international 20160128
Quercetin and phenylpropanoids are well known chemoprotective compounds identified in many plants. This study was aimed at determining their effects on activation of Nuclear factor erythroid 2-related factor 2 (Nrf2) antioxidant response element (Nrf2-ARE) signalling pathway and expression of its important downstream effector phase II detoxification enzyme glutathione-S-transferase P1 (GSTP1) in BJ foreskin fibroblasts and skin HaCaT keratinocytes. Cell lines and their corresponding Nrf2-ARE luc ...[more]