Computational high-resolution optical imaging of the living human retina.

ABSTRACT: High-resolution in vivo imaging is of great importance for the fields of biology and medicine. The introduction of hardware-based adaptive optics (HAO) has pushed the limits of optical imaging, enabling high-resolution near diffraction-limited imaging of previously unresolvable structures^1,2. In ophthalmology, when combined with optical coherence tomography, HAO has enabled a detailed three-dimensional visualization of photoreceptor distributions^3,4 and individual nerve fibre bundles⁵ in the living human retina. However, the introduction of HAO hardware and supporting software adds considerable complexity and cost to an imaging system, limiting the number of researchers and medical professionals who could benefit from the technology. Here we demonstr

SUBMITTER: Shemonski ND 

PROVIDER: S-EPMC4750047 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature