Can we stop prostate specific antigen testing 10 years after radical prostatectomy?

ABSTRACT:

Purpose

The risk of biochemical recurrence is inversely related to the relapse-free interval after radical prostatectomy. We examined predictors of late biochemical recurrence, and the relationship between timing of biochemical recurrence and long-term survival outcomes.

Materials and methods

Of 10,609 men treated with radical prostatectomy 1,684 had biochemical recurrence. We examined predictors of late biochemical recurrence (more than 10 years after radical prostatectomy), and calculated metastasis-free and cancer specific survival rates from the time of biochemical recurrence. In the subset of 1,583 men with an undetectable prostate specific antigen at 10 years we calculated actuarial metastasis-free and cancer specific survival estimates at 20 years after radical prosta

SUBMITTER: Loeb S 

PROVIDER: S-EPMC4750470 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature