Multinational Assessment of Accuracy of Equations for Predicting Risk of Kidney Failure: A Meta-analysis.

ABSTRACT:

Importance

Identifying patients at risk of chronic kidney disease (CKD) progression may facilitate more optimal nephrology care. Kidney failure risk equations, including such factors as age, sex, estimated glomerular filtration rate, and calcium and phosphate concentrations, were previously developed and validated in 2 Canadian cohorts. Validation in other regions and in CKD populations not under the care of a nephrologist is needed.

Objective

To evaluate the accuracy of the risk equations across different geographic regions and patient populations through individual participant data meta-analysis.

Data sources

Thirty-one cohorts, including 721,357 participants with CKD stages 3 to 5 in more than 30 countries spanning 4 continents, were studied. These cohorts collecte

SUBMITTER: Tangri N 

PROVIDER: S-EPMC4752167 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature