Physiological Contribution in Spontaneous Oscillations: An Approximate Quality-Assurance Index for Resting-State fMRI Signals.

ABSTRACT: Resting-state fMRI (rs-fMRI) is receiving substantial attention for its sensitivity to functional abnormality in the brain networks of people with psychiatric and neurological disorders. However, because of the variety of rs-fMRI processing methods, the necessity of rs-fMRI quality assurance is increasing. Conventionally, the temporal signal-to-noise ratio (tSNR) is generally adopted for quality examination, but the tSNR does not guarantee reliable functional connectivity (FC) outcomes. Theoretically, intrinsic FC is supposed to reflect the spontaneous synchronization of neuronal basis, rather than that from thermal noise or non-neuronal physiological noise. Therefore, we proposed a new quality-assurance index for rs-fMRI to estimate the physiological contributions in spontaneous oscillati

SUBMITTER: Hsu AL 

PROVIDER: S-EPMC4752279 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature