Pregnancy course and outcomes in women with arrhythmogenic right ventricular cardiomyopathy.

ABSTRACT:

Objectives

To characterise pregnancy course and outcomes in women with arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C).

Methods

From a combined Johns Hopkins/Dutch ARVD/C registry, we identified 26 women affected with ARVD/C (by 2010 Task Force Criteria) during 39 singleton pregnancies >13 weeks (1-4 per woman). Cardiac symptoms, treatment and episodes of sustained ventricular arrhythmias (VAs) and heart failure (HF) ≥ Class C were characterised. Obstetric outcomes were ascertained. Incidence of VA and HF were compared with rates in the non-pregnant state. Long-term disease course was compared with 117 childbearing-aged female patients with ARVD/C who had not experienced pregnancy with ARVD/C.

Results

Treatment during pregnancy (n=39) included β blo

SUBMITTER: Hodes AR 

PROVIDER: S-EPMC4752646 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature