Ontology highlight
ABSTRACT:
SUBMITTER: Sawyer AJ
PROVIDER: S-EPMC4753140 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Sawyer Andrew J AJ Kyriakides Themis R TR
Advanced drug delivery reviews 20160104
Extracellular matrix is composed of a complex array of molecules that together provide structural and functional support to cells. These properties are mainly mediated by the activity of collagenous and elastic fibers, proteoglycans, and proteins such as fibronectin and laminin. ECM composition is tissue-specific and could include matricellular proteins whose primary role is to modulate cell-matrix interactions. In adults, matricellular proteins are primarily expressed during injury, inflammatio ...[more]