A single generation of domestication heritably alters the expression of hundreds of genes.

ABSTRACT: The genetic underpinnings associated with the earliest stages of plant and animal domestication have remained elusive. Because a genome-wide response to selection can take many generations, the earliest detectable changes associated with domestication may first manifest as heritable changes to global patterns of gene expression. Here, to test this hypothesis, we measured differential gene expression in the offspring of wild and first-generation hatchery steelhead trout (Oncorhynchus mykiss) reared in a common environment. Remarkably, we find that there were 723 genes differentially expressed between the two groups of offspring. Reciprocal crosses reveal that the differentially expressed genes could not be explained by maternal effects or by chance differences in the background levels of ge

SUBMITTER: Christie MR 

PROVIDER: S-EPMC4757788 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature