A naphthalimide derived fluorescent sensor for solid-phase screening of cucurbit[7]uril-guest interactions.

ABSTRACT: A naphthalimide based fluorescent sensor displaying a significant increase in emission upon binding CB[7] with notable pH stability was developed and utilized in a surface-bound displacement assay for the rapid detection of CB[7] encapsulation of therapeutically relevant drug classes. Previously unknown binders with moderate to strong affinities were discovered.

SUBMITTER: Aryal GH 

PROVIDER: S-EPMC4758230 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature