First oncolytic virus approved for melanoma immunotherapy.

ABSTRACT: On 2015, October 27th, the US Food and Drug Administration (FDA) has officially approved talimogene laherparepvec (T-VEC, also known as OncoVEX^GM-CSF) for use in melanoma patients with injectable but non-resectable lesions in the skin and lymph nodes. T-VEC (which is commercialized by Amgen, Inc. under the name of Imlygic®) becomes therefore the first oncolytic virus approved for cancer therapy in the US.

SUBMITTER: Pol J 

PROVIDER: S-EPMC4760283 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature