Depression and telomere length: A meta-analysis.

ABSTRACT:

Background

Several recent studies have investigated the relationship between telomere length and depression with inconsistent results. This meta-analysis examined whether telomere length and depression are associated and explored factors that might affect this association.

Methods

Studies measuring telomere length in subjects with clinically significant unipolar depression were included. A comprehensive search strategy identified studies in PubMed, MEDLINE, PsycINFO, Global Health, The Cochrane Library, and Web of Science. A structured data abstraction form was used and studies were appraised for inclusion or exclusion using a priori conditions. Analyses were conducted using standardized mean differences in a continuous random effects model.

Results

Thirty-eight studi

SUBMITTER: Ridout KK 

PROVIDER: S-EPMC4760624 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature