Genomic reconstruction of the history of extant populations of India reveals five distinct ancestral components and a complex structure.

ABSTRACT: India, occupying the center stage of Paleolithic and Neolithic migrations, has been underrepresented in genome-wide studies of variation. Systematic analysis of genome-wide data, using multiple robust statistical methods, on (i) 367 unrelated individuals drawn from 18 mainland and 2 island (Andaman and Nicobar Islands) populations selected to represent geographic, linguistic, and ethnic diversities, and (ii) individuals from populations represented in the Human Genome Diversity Panel (HGDP), reveal four major ancestries in mainland India. This contrasts with an earlier inference of two ancestries based on limited population sampling. A distinct ancestry of the populations of Andaman archipelago was identified and found to be coancestral to Oceanic populations. Analysis of ancestral haploty

SUBMITTER: Basu A 

PROVIDER: S-EPMC4760789 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature