Differential frequency modulation of neural activity in the lateral cerebellar nucleus in failed and successful grasps.

ABSTRACT: The olivo-cerebellar system has an essential role in the detection and adaptive correction of movement errors. While there is evidence of an error signal in the cerebellar cortex and inferior olivary nucleus, the deep cerebellar nuclei have been less thoroughly investigated. Here, we recorded local field potential activity in the rodent lateral cerebellar nucleus during a skilled reaching task and compared event-related changes in neural activity between unsuccessful and successful attempts. Increased low gamma (40-50 Hz) band power was present throughout the reach and grasp behavior, with no difference between successful and unsuccessful trials. Beta band (12-30 Hz) power, however, was significantly increased in unsuccessful reaches, compared to successful, throughout the trial, including

SUBMITTER: Cooperrider J 

PROVIDER: S-EPMC4761293 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature