Order-Order Morphological Transitions for Dual Stimulus Responsive Diblock Copolymer Vesicles.

ABSTRACT: A series of non-ionic poly(glycerol monomethacrylate)-poly(2-hydroxypropyl methacrylate) (PGMA-PHPMA) diblock copolymer vesicles has been prepared by reversible addition-fragmentation chain transfer (RAFT) aqueous dispersion polymerization of HPMA at 70 °C at low pH using a carboxylic acid-based chain transfer agent. The degree of polymerization (DP) of the PGMA block was fixed at 43, and the DP of the PHPMA block was systematically varied from 175 to 250 in order to target vesicle phase space. Based on our recent work describing the analogous PGMA-PHPMA diblock copolymer worms [Lovett J. R.; Angew. Chem.2015, 54, 1279-1283], such diblock copolymer vesicles were expected to undergo an order-order morphological transition via ionization of the carboxylic acid end-group on swit

SUBMITTER: Lovett JR 

PROVIDER: S-EPMC4762544 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature