Comparison of iron status 28 d after provision of antimalarial treatment with iron therapy compared with antimalarial treatment alone in Ugandan children with severe malaria.

ABSTRACT:

Background

The provision of iron with antimalarial treatment is the standard of care for concurrent iron deficiency and malaria. However, iron that is given during a malaria episode may not be well absorbed or used, particularly in children with severe malaria and profound inflammation.

Objectives

We aimed to 1) determine baseline values of iron and inflammatory markers in children with severe malarial anemia (SMA), children with cerebral malaria (CM), and community children (CC) and 2) compare markers in iron-deficient children in each group who received 28 d of iron supplementation during antimalarial treatment with those in children who did not receive iron during treatment..

Design

Seventy-nine children with CM, 77 children with SMA, and 83 CC who presented to Mul

SUBMITTER: Cusick SE 

PROVIDER: S-EPMC4763490 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature