Effect of zinc and multivitamin supplementation on the growth of Tanzanian children aged 6-84 wk: a randomized, placebo-controlled, double-blind trial.

ABSTRACT:

Background

Poor child growth increases risks of mortality and morbidity. Micronutrient supplements have the potential to improve child growth.

Objective

We assessed the effect of daily zinc, multivitamin (vitamins C, E, and B-complex), and zinc and multivitamin (Zn+MV) supplementation on growth in infants in Tanzania.

Design

In this randomized, 2 × 2 factorial, double-blind trial, 2400 infants were randomly assigned to receive zinc, multivitamins, Zn+MVs, or a placebo at 6 wk of age and were followed up for 18 mo with monthly growth measurements. Mixed-effects models with restricted cubic splines for the mean change in anthropometric z scores were fit for each group. Likelihood ratio tests were used to compare the effect of supplements on growth trajectories. Cox prop

SUBMITTER: Locks LM 

PROVIDER: S-EPMC4763494 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature