Rs401681 polymorphism in TERT-CLPTM1L was associated with bladder cancer risk: A meta-analysis.

ABSTRACT:

Objectives

Genome-wide association studies have identified a number of genetic variants of telomerase reverse transcriptase (TERT), cleft lip and palate transmembrane1-like (CLPTM1L) associated with the risk of bladder cancer. Rs401681 polymorphism in TERT-CLPTM1L was of special interest for bladder cancer risk, whereas the results were inconclusive.

Materials and methods

Publications illustrating the association between rs401681 polymorphism and bladder cancer risk were collected from the Embase, PubMed and Google scholar. Three independent reviewers worked on the data extraction. The meta-analysis was performed by STATA 12.0. The odds ratio (OR) with 95% confidence interval (CI) was calculated for these data.

Results

Six case-control studies were retrieved reporting

SUBMITTER: Zhang M 

PROVIDER: S-EPMC4764116 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature