Intact Acquisition and Short-Term Retention of Non-Motor Procedural Learning in Parkinson's Disease.

ABSTRACT: Procedural learning is a form of memory where people implicitly acquire a skill through repeated practice. People with Parkinson's disease (PD) have been found to acquire motor adaptation, a form of motor procedural learning, similarly to healthy older adults but they have deficits in long-term retention. A similar pattern of normal learning on initial exposure with a deficit in retention seen on subsequent days has also been seen in mirror-reading, a form of non-motor procedural learning. It is a well-studied fact that disrupting sleep will impair the consolidation of procedural memories. Given the prevalence of sleep disturbances in PD, the lack of retention on following days seen in these studies could simply be a side effect of this well-known symptom of PD. Because of this, we wondere

SUBMITTER: Panouilleres MT 

PROVIDER: S-EPMC4764369 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature