Difference in 24-Hour Urine Composition between Diabetic and Non-Diabetic Adults without Nephrolithiasis.

ABSTRACT:

Background

Diabetic patients are more likely to develop kidney stones than the general population. The underlying mechanisms for this disparity remain to be elucidated. Little is known about the relationship between urine composition and diabetes mellitus in non-stone-forming individuals. We sought to examine the differences in the 24-hour (24-h) urine composition between diabetic and non-diabetic adults who were not stone formers.

Methods

A convenience sample of 538 individuals without a history of nephrolithiasis, gout, hyperparathyroidism, or gastroenteric diseases participated in this study. The 24-h urine profiles of 115 diabetic adults were compared with those of 423 non-diabetic adults. Diabetes was defined by self-reported physician diagnosis or medication use. All p

SUBMITTER: Zhu W 

PROVIDER: S-EPMC4764372 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature