Chronic medical conditions in adult survivors of retinoblastoma: Results of the Retinoblastoma Survivor Study.

ABSTRACT:

Background

Limited data are available regarding long-term morbidity in adult survivors of retinoblastoma (Rb).

Methods

The Retinoblastoma Survivor Study is a retrospective cohort of adult survivors of Rb diagnosed between 1932 and 1994. Participants completed a comprehensive questionnaire adapted from the Childhood Cancer Survivor Study surveys. Chronic conditions were classified using the National Cancer Institute's Common Terminology Criteria for Adverse Events (version 4.03). Multivariate Poisson regression was used to compare survivors of Rb with 2377 non-Rb controls, consisting of the Childhood Cancer Survivor Study sibling cohort and survivors with bilateral versus unilateral disease.

Results

Survivors of Rb (53.6% with bilateral disease) and non-Rb controls had

SUBMITTER: Friedman DN 

PROVIDER: S-EPMC4764449 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature