The Brain Network of Naming: A Lesson from Primary Progressive Aphasia.

ABSTRACT:

Objective

Word finding depends on the processing of semantic and lexical information, and it involves an intermediate level for mapping semantic-to-lexical information which also subserves lexical-to-semantic mapping during word comprehension. However, the brain regions implementing these components are still controversial and have not been clarified via a comprehensive lesion model encompassing the whole range of language-related cortices. Primary progressive aphasia (PPA), for which anomia is thought to be the most common sign, provides such a model, but the exploration of cortical areas impacting naming in its three main variants and the underlying processing mechanisms is still lacking.

Methods

We addressed this double issue, related to language structure and PPA, with t

SUBMITTER: Migliaccio R 

PROVIDER: S-EPMC4764674 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature