High Resolution Topography of Age-Related Changes in Non-Rapid Eye Movement Sleep Electroencephalography.

ABSTRACT: Sleeping brain activity reflects brain anatomy and physiology. The aim of this study was to use high density (256 channel) electroencephalography (EEG) during sleep to characterize topographic changes in sleep EEG power across normal aging, with high spatial resolution. Sleep was evaluated in 92 healthy adults aged 18-65 years old using full polysomnography and high density EEG. After artifact removal, spectral power density was calculated for standard frequency bands for all channels, averaged across the NREM periods of the first 3 sleep cycles. To quantify topographic changes with age, maps were generated of the Pearson's coefficient of the correlation between power and age at each electrode. Significant correlations were determined by statistical non-parametric mapping. Absolute slow wa

SUBMITTER: Sprecher KE 

PROVIDER: S-EPMC4764685 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature