High-sensitivity cardiac troponin I at presentation in patients with suspected acute coronary syndrome: a cohort study.

ABSTRACT:

Background

Suspected acute coronary syndrome is the commonest reason for emergency admission to hospital and is a large burden on health-care resources. Strategies to identify low-risk patients suitable for immediate discharge would have major benefits.

Methods

We did a prospective cohort study of 6304 consecutively enrolled patients with suspected acute coronary syndrome presenting to four secondary and tertiary care hospitals in Scotland. We measured plasma troponin concentrations at presentation using a high-sensitivity cardiac troponin I assay. In derivation and validation cohorts, we evaluated the negative predictive value of a range of troponin concentrations for the primary outcome of index myocardial infarction, or subsequent myocardial infarction or cardiac death at

SUBMITTER: Shah AS 

PROVIDER: S-EPMC4765710 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature