Silent Brain Infarction and Risk of Future Stroke: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background and purpose

Silent brain infarction (SBI) on magnetic resonance imaging has been proposed as a subclinical risk marker for future symptomatic stroke. We performed a systematic review and meta-analysis to summarize the association between magnetic resonance imaging-defined SBI and future stroke risk.

Methods

We searched the medical literature to identify cohort studies involving adults with SBI detected by magnetic resonance imaging who were subsequently followed up for incident clinically defined stroke. Study data and quality assessment were recorded in duplicate with disagreements in data extraction resolved by a third reader. Strength association between magnetic resonance imaging-detected SBI and future symptomatic stroke was measured by an hazard ratio.

Re

SUBMITTER: Gupta A 

PROVIDER: S-EPMC4766016 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature