Quantification of myocardial blood flow using non-electrocardiogram-triggered MRI with three-slice coverage.

ABSTRACT:

Purpose

Accurate quantification of myocardial perfusion is dependent on reliable electrocardiogram (ECG) triggering. Measuring myocardial blood flow (MBF) in patients with arrhythmias or poor ECGs is currently infeasible with MR. The purpose of this study was to demonstrate the feasibility of a non-ECG-triggered method with clinically useful three-slice ventricular coverage for measurement of MBF in healthy volunteers.

Methods

A saturation recovery magnetization-prepared gradient recalled echo acquisition was continuously repeated during first-pass imaging. A slice-interleaved radial trajectory was employed to enable image-based retrospective triggering. The arterial input function was generated using a beat-by-beat T1 estimation method. The proposed technique was validated

SUBMITTER: Chen D 

PROVIDER: S-EPMC4766039 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature