Adherence therapy versus routine psychiatric care for people with schizophrenia spectrum disorders: a randomised controlled trial.

ABSTRACT:

Background

Current practice guidelines for schizophrenia care recommend that antipsychotic medication is essential for patients' long-term maintenance treatment but their non-adherence to this medication is still a main obstacle to relapse prevention. This study evaluated the effects of a motivational-interviewing-based adherence therapy for people with schizophrenia spectrum disorders.

Methods

This randomised controlled trial was conducted with 134 outpatients with schizophrenia spectrum disorders; 67 of them received a six-session adherence therapy (in addition to usual care) and 67 received usual psychiatric care alone. Participants' outcome measures included symptom severity, medication adherence, hospitalisation rates, insight into illness/treatment, and functioning.

SUBMITTER: Chien WT 

PROVIDER: S-EPMC4766670 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature