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Longitudinal changes in resting-state fMRI from age 5 to age 6years covary with language development.


ABSTRACT: Resting-state functional magnetic resonance imaging is a powerful technique to study the whole-brain neural connectivity that underlies cognitive systems. The present study aimed to define the changes in neural connectivity in their relation to language development. Longitudinal resting-state functional data were acquired from a cohort of preschool children at age 5 and one year later, and changes in functional connectivity were correlated with language performance in sentence comprehension. For this, degree centrality, a voxel-based network measure, was used to assess age-related differences in connectivity at the whole-brain level. Increases in connectivity with age were found selectively in a cluster within the left posterior superior temporal gyrus and sulcus (STG/STS). In order to fur

SUBMITTER: Xiao Y 

PROVIDER: S-EPMC4767215 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature