Sleep Duration and Disruption and Prostate Cancer Risk: a 23-Year Prospective Study.

ABSTRACT:

Background

Sleep deficiency is a major public health problem. There are limited human data on whether sleep duration or disruption are risk factors for prostate cancer.

Methods

We prospectively followed 32,141 men in the Health Professionals Follow-Up Study who reported their typical sleep duration in 1987, 2000, and 2008. We identified 4,261 incident prostate cancer cases, including 563 lethal cases through 2010. Sleep disruption was assessed in 2004 among 19,639 men, with 930 prostate cancer cases (50 lethal) identified from 2004 to 2010. Cox proportional hazards models were used to evaluate the association between sleep insufficiency and risk of overall and lethal prostate cancer.

Results

In 1987, 2% of men reported sleeping ≤5 hours per night. We found no associat

SUBMITTER: Markt SC 

PROVIDER: S-EPMC4767658 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature