An inferential study of the phenotype for the chromosome 15q24 microdeletion syndrome: a bootstrap analysis.

ABSTRACT: In January 2012, a review of the cases of chromosome 15q24 microdeletion syndrome was published. However, this study did not include inferential statistics. The aims of the present study were to update the literature search and calculate confidence intervals for the prevalence of each phenotype using bootstrap methodology. Published case reports of patients with the syndrome that included detailed information about breakpoints and phenotype were sought and 36 were included. Deletions in megabase (Mb) pairs were determined to calculate the size of the interstitial deletion of the phenotypes studied in 2012. To determine confidence intervals for the prevalence of the phenotype and the interstitial loss, we used bootstrap methodology. Using the bootstrap percentiles method, we found wide vari

SUBMITTER: Palazon-Bru A 

PROVIDER: S-EPMC4768676 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature