Pharmacogenetics of healthy volunteers in Puerto Rico.

ABSTRACT: Puerto Ricans are a unique Hispanic population with European, Native American (Taino), and higher West African ancestral contributions than other non-Caribbean Hispanics. In admixed populations, such as Puerto Ricans, genetic variants can be found at different frequencies when compared to parental populations and uniquely combined and distributed. Therefore, in this review, we aimed to collect data from studies conducted in healthy Puerto Ricans and to report the frequencies of genetic polymorphisms with major relevance in drug response. Filtering for healthy volunteers or individuals, we performed a search of pharmacogenetic studies in academic literature databases without limiting the period of the results. The search was limited to Puerto Ricans living in the island, excluding those stu

SUBMITTER: Claudio-Campos K 

PROVIDER: S-EPMC4768757 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature